Asthma Article Published In: thefamilygroove.com

http://thefamilygroove.com/apr09_EveryBreathYouTake.htm

EVERY BREATH YOU TAKE
DR. ANATOLY BELILOVSKY, MD, ANSWERS YOUR ASTHMA FAQS AND TALKS
OUTDOOR POLLUTION, ALTERNATIVE TREATMENT AND STRESS

Every Breath You TakeQ: What is asthma, really?
A: Asthma is the reversible narrowing of bronchi,
the pipes through which air reaches your lungs.
Look at it this way: Imagine breathing through
your eyes. Have you heard of bronchospasm?
That’d be like your eye was closed. Bronchial
inflammation? That’d be like your eye was swollen
shut and filled with gunk. Reversible obstruction? That’d be like your eye was shut one minute (a trigger response) and wide open the next.

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Q: Why is there so much asthma lately?
A: The theory that makes the most sense, and is best backed up by evidence, is the hygiene hypothesis. In several studies, it was found that in developing countries, people who were infested by intestinal parasites had less allergy and asthma than those who were not, and in a German study, less asthma was found in children who survived a life-threatening infection. The immune system is constantly on the lookout for infections and parasites and, lacking real targets for the immune cells to attack, sometimes attacks healthy tissues or overreacts to minor infections. There are a number of infectious agents such as respiratory syncytial virus or mycoplasma that have been identified as commonly associated with asthma, and, of course, pollutants can trigger attacks. Blaming all asthma on outdoor pollution is probably incorrect, as the air is cleaner now than it has been for hundreds of years because of stricter environmental controls.

Q: How is asthma treated?
A: There are medications like albuterol, which relaxes the muscles holding the airway closed; steroids, which decrease the swelling; and antibiotics, which treat the infections that may either trigger or complicate asthma episodes. A common mistake is to assume that, if shortness of breath is absent, all is well. This error is best avoided with the use of a little toy called a peak flow meter. It measures how fast you can breathe out, compared with both your personal best and the ideal calculated for your age and height. Peak flow numbers will drop long before actual shortness of breath appears, allowing you to adjust your treatment or seek help early. Another dangerous mistake is to treat with beta-agonists (like albuterol) alone. They work quickly, but in the worst attacks, they fail without warning; dependence on beta-agonists has caused many deaths in asthmatics. Think of them as fire extinguishers; if you use one daily, there is something wrong in your kitchen, and they are useless against a big fire. There are a number of preventive medications that keep attacks from happening, and a number of rescue medications that stop breakthrough attacks, but the old “can’t breathe, take a puff” routine is not only useless, but potentially deadly.

Q: What are alternative treatments for asthma?
A: First of all, emotional distress is a well-known asthma trigger. The lungs and the brain are connected by the vagus nerve, and vagus activity is known to produce asthma attacks, so whatever makes you feel less anxiety will probably have an effect against asthma. Secondly, a number of plants produce toxins that, in small quantities, have an asthma-blocking activity. Unfortunately, as these toxins are needed by the plants to keep them from being eaten by animals, they tend to have serious side effects. Ephedrine in ma huang, theophylline in tea, and scopolamine in deadly nightshade are examples of such poisons. Many currently used medications are “declawed,” less toxic derivatives of natural plant poisons. Thirdly, human and animal adrenal glands produce steroid hormones, some of which fight the inflammation that is part of an asthmatic event. Both natural versions of these hormones and synthetic derivatives are used sparingly, as they produce their effect by suppression of immunity. “Declawed” versions of these hormones are easily destroyed in the bloodstream; they are given as inhalations directly into the airways and do not produce measurable effects anywhere else in the body.

Physical activity appears to help more often than not; exercise-induced asthma appears to be less common than asthma that gets better with consistent exercise. In any case, asthma should never serve as an excuse for reduced activity. Finally, anything that controls heartburn will probably reduce asthma severity as well—and since caffeine, fat, overeating, spicy foods, alcohol, smoking and tight clothing can all induce heartburn, avoiding them might be worth a try.

Dr. Anatoly Belilovsky is a New York pediatrician whose 365-day practice, Belilovsky Pediatrics, won an AmeriChoice award for Center of Excellence in asthma care. He is a graduate of Princeton University and served as a clinical instructor in pediatrics at Cornell’s Weill Medical College. For more information, visit his website and blog www.babydr.us.

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Swine Flu 4.3: I know karate, kung-fu, kendo, and many other scary words

Another exciting weekend went by, families less anxious I think than before (must be watching Fox News and Telemundo); Saturday 5/2/09 — 3 positive Flu A, 4 positive for Strep Throat; Today, Sunday 5/3/09 — 1 positive Flu A, 13 (!) positive for Strep Throat.  Let’s not ignore Group A Beta Hemolytic Streptococcus pyogenes (the active ingredient in strep throat) — people die of strep.  George Washington did, as did Jim Henson and Lou Costello. People who have Strep get treated and followed up, just like children with flu.
Seriously, folks, we may be nearing the end of this hysteria. A Hong Kong hotel may still be sealed with people in it as you read this,  but here in New York, most people seem aware of swine flu being common and moderate rather than rare and severe; not so much snakes on a plane as geese in front of one.  If I helped any, I’m happy.  If you look at other stories from Tuesday 4/28 (when I had my radio interviews) and Wednesday 4/29 (when I was on Telemundo and Fox News), they tend to be far more alarmist.  Infections are, generally, not good for you.  Nature is not our friend; it is, at best, a disinterested observer in our ongoing disputes with the sabretooth tiger (which we won), Rickettsia rickettsii (which we are winning), and the human immunodeficiency virus (which is down but not out).  Should there ever be a real reason for elevated concern, watch this space: I will then –

“Cry havoc, and let slip the dogs of war”.

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Swine Flu 4.2: Acute postprandial upper abdominal distention

In yet another Star trek reference, words spoken by Dr McCoy to create a sense of extreme urgency — actually mean “eating too much”: “acute” = (of disease) brief and severe; “postprandial” = after a meal; “upper abdominal” relating to the area of the stomach; “distension” = the state of being stretched beyond normal dimensions.  And, yes, I am enjoying paying homage to the TV show from which I learned spoken English.  And, yes, “deadly”, “swine”, and “pandemic” are being thrown around with abandon to create a panic that need not happen.  “Deadly” may apply to anything of which anyone ever died (and, in a rather confusing email from CDC, I learned that apparently the Mexican confirmed swine flu death toll is downgraded to… 7…?

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm58d0430a2.htm?s_cid=mm58d0430a2_e

Well, that’s way below what seasonal flu causes every season, but, technically still deadly.

Calling it “swine” (or “bird”) flu is also misleading, as most new strains are produced by reassortment in pigs and poultry in close contact passing the infection back and forth; and a “pandemic” means the whole world is sick with it — which applies equally well to common cold and athlete’s foot.  Reminds me of the obsessive-compulsive agnostic dyslexic insomniac — stays up all night wondering if there is a dog.

Anyway, only one positive yesterday (out of a many many anxious families) and that one not very sick either.  “Acute postprandial upper abdominal distention” also means being fed up, and it seems that the media have had their fill of hysteria, and voices of sanity are beginning to prevail:

http://www.nytimes.com/2009/05/02/health/02flu.html?ref=americas

Five days after my interview with a Miami radio station:…

http://www.youtube.com/watch?v=AU0oom3B8DM

…and the Fox News TV interview:

http://www.foxnews.com/search-results/m/22200273/swine-flu-reality.htm 

… most news and official statements are beginning to confirm what we saw.

As a training exercise, or a dress rehearsal, for handling a really severe outbreak (which this was not), the official response to this epidemic has been of great value.  I think it will be analysed for years to come to assure better preparation for a potential emergency.  So for local, state, federal and international health authorities I have nothing but praise (especially let’s give a big hand to NYC Health Department, whose actions were an incredibly short 24 hours behind the frontline view).  I am less happy about the media; this is not the time to be crying “wolf”, no matter how it improves sales, ratings, or hit counts.  Let’s save the hyperbole for when we need it.

In case anyone forgot, Star Trek V is titled “The Final Frontier”; I don’t think the flu story has a final anything in it, so I’ll stay with 4.x for the time being.

Once I post them, click “Comments” for my videos on the swine flu subject.

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Swine Flu 4.1: The Perfect Storm?

Our Flu A (highly likely swine flu) count is now up to 8, 2 more coming in yesterday and being diagnosed by a rapid test, and the more I think about the Mexico death toll, the more likely it seems that a perfect storm of risk factors is responsible.  The most dramatic example of a perfect storm is a cancer called Burkitt’s lymphoma, common in Equatorial Africa but rare in African Americans.  It turned out that a combination of a gene mutation, malaria and Epstein-Barr virus infection is necessary to trigger it, and only in Africa do the 3 factors (each common elsewhere) come together.  The 1976 Swine flu outbreak went nowhere outside a basic training cadre in a military base — it is theorized that a packed-in crowd of stressed-out individuals created the fertile environment not duplicated elsewhere (outside of most middle schools I know).  And, the great mathematician Srinivasan Ramanujan, deprived of vitamins A and D by his dark skin, living in sun-starved England, and vegetarian diet, succumbed to tuberculosis after being thus weakened.  I have already mentioned my thoughts on risk factors possibly prevalent in Mexico; iron deficiency, in particular, is common in my patients from Mexican families, and may contribute as well.  I am sure that is being thoroughly investigated, and more than one risk factor may be responsible, delineating areas of concern for other countries.  In the meantime, we should go about out lives, washing our hands perhaps more often and going into crowds perhaps a bit less, and as for vitamin supplements — make sure A and D are in them.

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Swine Flu IV: The Voyage (that the virus already made to our) Home

Three more Flu A cases yesterday, only one (a Mexican teenager) looking sick enough to suspect flu, but nowhere near life-threatening.  Called NYC Health Department.  Guess what?  They agree with me!  They think all new Flu A is swine flu; they agree that it is less severe than “regular” flu; they think the cases in the city are too numerous to count or confirm, and that many are so mildly ill that they will never even see a doctor; they do NOT want me to report cases or send samples for confirmation UNLESS the patient is sick enough to be hospitalized (which is perfectly reasonable, if they try to count every sniffle in New York they will have no time left for their real jobs dealing with life threatening disease).  Channel 7 News at 11 interviewed me yesterday and this is pretty much what I told them; either I was too boring or what I said was too boring, and they chose not to run my segment, opting instead for more exciting news of school closings and masks running out in pharmacies all over town.  This being the case, I will enlist professional help in bringing my message to the public: (click on the Comments link below):

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Swine Flu III: The Search for Snot

(Diagnosis is made by analysis of nasopharyngeal secretions, you see.  It’s a pun.  It’s supposed to be funny.  You may laugh when ready.)

Here’s a draft of an interview I gave on Swine Flu as it impacts new mothers:

> 1)  What exactly is swine flu?

It’s a flu previously only seen in pigs.  IN fact, all flu strains arise
in pigs and poultry, and cause human epidemics when they become
transmissible between humans.
>
>
>
> 2)  New moms may have added concerns over the current swine flu threat.
> What should a new mom know about swine flu in regards to her baby?

The “additional” concern is really only for families that received the flu
vaccines as recommended by the CDC, because the seasonal flu shots do not
appear to prevent this new strain.  For people who were not immunized this
season, the garden variety, “regular” flu is probably still the greater
threat, with thousands of fatalities in US.
>
>
> 3)  How serious is the swine flu in regard to small infants? Are some
> infants more susceptible than others?

Possibly; the only place where serious cases have occurred so far is
Mexico, and the risk factors are still being analyzed there.
>
>
>
> 4)  What precautions should a mom take to keep her baby healthy?

Keep out of crowds, wash hands and everything else that touches a baby.
Vitamins A and D should be supplemented, especially in breastfeeding
babies over 2 months age and all mothers, as they are vital in maintaining
appropriate immune response, and are most often deficient.
>
>
>
> 5)  What symptoms should she keep an eye out for in her baby and when
> should she seek medical attention for her baby if she suspects swine flu
> contact?
>

The usual — fever, cough, poor appetite, cranky or lethargic, looking sick.
>
>
> 6)  If an infant does contract swine flu, what is the treatment?

Tamiflu appears to be effective; you and your doctor will decide if it is
appropriate.
>
>
>
> 7)  Is there anything I have forgotten or that you would to add to the
> topic?

The early returns suggest that this is a milder disease than regular flu,
amd is probably very widespread already, with lots of mildly sick people
running around, going about their business, and getting better without
ever being diagnosed with swine flu.  In fact, the countries reporting
cases now are those with real-time capability of analyzing virus genome to
identify it, and I doubt anyone is spending the money to test mildly ill
persons.  We will soon know why Mexican patients are more severely
affected; possibility include genetic (Native Americans appear to have
different immune response to certain infections), vitamin deficiencies, a
pool of infected individuals well into the millions leading to fatality in
a rather small percentage of cases, existence of a co-infection in Mexico,
and toxic folk remedies or counterfeit medications.
>
>

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Swine Flu II: The Wrath of Ham

OK, here is what happened today:

3 children tested positive for Flu A.  2 of them had been immunized with Flumist, which up till now only rarely failed (maybe 5 previous positive Flu A’s out of hundreds previously immunized children tested).  The 3rd child was not immunized.  NONE of the 3 had “severe” flu — none had high fever, none looked as miserable as actors in NyQuil advertisements, none had anything resembling complications — in fact, in the middle of the epidemic 2 months ago, I probably would not have tested them because they did not look sick enough to have the “real” (garden variety) flu.  I gave Tamiflu to all three, and will follow them closely.  I do not know for sure that they had “swine” flu, but it is unlikely that “garden variety” flu would produce equally mild disease in immunized and unimmunized individuals.

So what is the most likely explanation?

I think this “new” swine flu is actually quite widespread already; I think the great majority of people who had it, never knew they had it because they did not feel sick enough to go to the doctor, and if they did, they did not look sick enough to be tested for flu.  I do not know what was different about the fatal cases in Mexico (apparently caused by the same virus), but I suspect we will find out soon.

Coming soon: Swine Flu III: The Search for Sanity…

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Swine Flu: The Muddled Picture

The good news is, as of right now it does not appear to be significantly more severe, more contagious, 
or more drug-resistant than garden variety flu, and the H1N1 component of previous flu vaccines may 
actually create at least a small immunity against the swine flu, so the need to worry about this epidemic
 is most pressing for chronically ill and/or elderly individuals who are at high risk for complications from 
any strain of influenza, with the added caveat that the flu shot they received this year may not offer 
them significant protection.
We are also continuing to test for flu in the office; today we have had 3 positive
for flu A so far. (2 PM, we are open 9am to 7pm).  I have to assume these are all
swine flu, as all "regular" flu activity lately has been "B".  None are very sick;
all are getting Tamiflu, with expectations that it will work.  If you are worried, we can help.
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In Praise of Allopathy

The brilliant water landing of US Airways Flight 1549 is out of immediate news lately, but hardly out of mind of all of us, especially those who work a loud shout away from the splashdown area. And looking at the interview with Captain Sullenberger, one cannot help but admire, and it with utmost admiration that I say, “It was such an allopathic thing to do!” Indeed, where a homeopathic approach would have required the Captain to flap his arms or to ask his passengers to face backwards and belch; where a public health approach would have requred him to fill out an environmental impact statement on the way down; where a holistic approach would have demanded that he address his passengers’ feelings with greater sensitivity and at length, and where a naturopathic practitioner would bemoan the fate of homogenized geese and claim the accident a just consequence for violating their airspace — Captain Sullenberger said, “Brace for impact”, and proceeded to execute a perfect, textbook dead stick water landing, using sound aerodynamic principles and skills honed by years of practice. And, to top it off, he checked, twice, to see to it that everyone escaped alive. And then he did not see what the big deal was about a guy doing his job. If there is a better metaphor for what medicine needs to emulate, I have not seen it. Not since Nine Eleven, anyway.

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Sic semper tyrannis?

The first time I was right in my predictions and wished I wasn’t, it was on a subject I already beat to death: immunizations. In the very early 1990′s, as the Soviet Union fell apart, one of the results of its decomposition was a drastic drop-off in immunizations. And, seeing, to my distress, dozens of recent immigrants with few to no immunizations, I spared no effort getting them caught up to US standards. In at least one case I was too late: a little girl died of measles encephalitis while in my care. This family’s tragedy was a pale shadow of the massive disaster that befell what was left of the Soviet Union: thousands of deaths of preventable disease, mainly whooping cough, measles and diphtheria, and hundreds of thousands experiencing pain or disability.

But his is not about pushing for more mandatory immunizations. Quite the contrary.

It is a historical fact that public health works best in efficient tyrannies. Godwin’s Law states that sooner or later, Nazis will be invoked in any online discussion, so I might as well get this out of the way early: Nazi Germany and Stalin’s USSR had the most effective public health systems in the world at the time. They weren’t necessarily good, as the former was used to kill the less-than-perfect children, the latter developed psychaitric techniques for mind control, and both experimented on the unwilling, but as far as delivering their concept of health care to the masses, no one could touch them. In both cases, the motive was the same — a healthy, procreating herd of workers to be used for war or industrial development as needed; the means — an enslaved workforce including medical personnel to be used at government’s discretion; and the opportunity — the ability to deliver health care to homes and schools and workplaces bypassing the annoying complication of informed consent. As anyone who knows history can appreciate, when tyrannies fall, power plants crumble before prisons; and as public health enforcement withered away, the public rebelled against immunizations as they did against marching in goosestep. The latter was free of consequences; the former was not.

It bothers me that, as we get increasingly safer and more effective immunizations in our arsenal, and more and more information demonstrating their safety, we get more and more families asking to opt out. I think this is happening because of increasing government mandates — both for the families to accede to every single immunization in the pharmacopeia, and for us to escalate pressure on the families to do so. Tyrannies do not encourage thought; they result in either bovine acquiescence or pigheaded rebellion, and neither is a considered choice. I bothers me equally to have my patients line up to obey the Authorities, or distrust me as the agent of the Authorities. I do my own thinking and I prefer you do the same. And I’d much rather call someone an idiot than turn them in as a neglectful parent. So if you think I insulted your intelligence in our recent discussion about immunizations, well, yes, that was my intent. But, all in all, I’d rather live in a country that has freedom of stupidity. I shudder to think of how a government might outlaw stupidity successfully.

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